Open AccessMorphometric Analysis of Colonic Adenomatous Polyps
Author(s) -
Tsuno Nelson,
Muto Tetsuichiro,
Kubota Yoshiro,
Sawada Toshio,
Nagawa Hirokazu
Publication year - 1993
Publication title -
japanese journal of cancer research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.035
H-Index - 141
eISSN - 1349-7006
pISSN - 0910-5050
DOI - 10.1111/j.1349-7006.1993.tb02872.x
Subject(s) - dysplasia , adenomatous polyps , malignancy , medicine , pathology , familial adenomatous polyposis , adenoma , index (typography) , colonoscopy , colorectal cancer , cancer , computer science , world wide web
Morphometric evaluation of adenomas of the colon to determine their degree of dysplasia is still controversial, since subjective factors influence the decision concerning benignancy or malignancy. Some indices have been proposed to assist in categorizing intermediate lesions into benign or malignant. However, these indices show a wide range of distribution. To evaluate the reliability of one such index, the index of structural atypism (ISA, area of glands/area of stroma), we studied polyps as a whole, and found great variability of index values within a single polyp.