Open AccessPresence of Human Papillomavirus Type 18 DNA in a Pharyngeal and a Laryngeal Carcinoma
Author(s) -
Ogura Hajime,
Watanabe Shuichi,
Fukushima Kunihiro,
Masuda Yu,
Fujiwara Tazuko,
Yoshiro Yoshiro
Publication year - 1991
Publication title -
japanese journal of cancer research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.035
H-Index - 141
eISSN - 1349-7006
pISSN - 0910-5050
DOI - 10.1111/j.1349-7006.1991.tb01776.x
Subject(s) - laryngeal neoplasm , polymerase chain reaction , carcinoma , pharynx , larynx , dna , epithelioma , pathology , human papillomavirus , papillomaviridae , biology , medicine , cancer , gene , anatomy , genetics , cervical cancer
We examined the presence of human papillomavirus (HPV) genome in pharyngeal and laryngeal squamous cell carcinomas by employing the polymerase chain reaction. We detected HPV 16 DNA in one of 11 pharyngeal carcinomas and in 3 of 28 laryngeal carcinomas, and HPV 18 DNA in a pharyngeal and a laryngeal carcinoma. In one of the laryngeal carcinomas, DNA of both HPV types 16 and 18 were detected. To our knowledge, this is the first report of detection of HPV type 18 in head and neck carcinomas.