Open AccessExpression of Membrane‐associated Lymphotoxin/Tumor Necrosis Factor‐β on Human Lymphokine‐activated Killer Cells
Author(s) -
Abe Yasuhito,
Miyake Masazumi,
Horiuchi Atsushi,
Kimura Shigeru,
Yasuo Yasuo
Publication year - 1991
Publication title -
japanese journal of cancer research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.035
H-Index - 141
eISSN - 1349-7006
pISSN - 0910-5050
DOI - 10.1111/j.1349-7006.1991.tb01740.x
Subject(s) - lymphotoxin , lymphokine , lymphotoxin alpha , lymphokine activated killer cell , antigenicity , tumor necrosis factor alpha , biology , immunology , lymphotoxin beta receptor , microbiology and biotechnology , chemistry , antigen , t cell , immune system , interleukin 21
A membrane‐associated lymphotoxin (LT)‐related molecule was detected on human lymphokine‐activated killer (LAK) cells by flow cytometric analysis. Kinetic analysis revealed that the LT antigenicity on LAK cells appeared at 9 h after the beginning of culture and was maintained thereafter. By autoradiography, the molecular weight of membrane LT was estimated to be 31 kD and/or 62 kD.