
No Evidence of HTLV‐1 Infection in Japanese Multiple Sclerosis Patients in Polymerase Chain Reaction
Author(s) -
Watanabe Toshiki,
Iwasaki Yuzo,
Tashiro Kunio,
Yoshida Mitsuaki
Publication year - 1989
Publication title -
japanese journal of cancer research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.035
H-Index - 141
eISSN - 1349-7006
pISSN - 0910-5050
DOI - 10.1111/j.1349-7006.1989.tb02251.x
Subject(s) - polymerase chain reaction , peripheral blood mononuclear cell , multiple sclerosis , virology , virus , leukemia , viral disease , real time polymerase chain reaction , dna , medicine , immunology , biology , gene , in vitro , genetics
To test possible association of human T cell leukemia virus type 1 (HTLV‐1) with multiple sclerosis (MS), polymerase chain reaction was applied to detect HTLV‐1 DNA integrated into peripheral blood mononuclear cell DNA. Nine Japanese MS patients all gave a negative result, indicating no HTLV‐1 infection in these MS patients.