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Impact of biocides on biofilm formation by methicillin‐resistant Staphylococcus aureus (ST239‐SCC mec III) isolates
Author(s) -
Aparecida Guimarães Marcia,
Rocchetto Coelho Leonardo,
Rodrigues Souza Raquel,
FerreiraCarvalho Bernadete Teixeira,
Marie Sá Figueiredo Agnes
Publication year - 2012
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.2011.00423.x
Subject(s) - biofilm , peracetic acid , sodium hypochlorite , biocide , microbiology and biotechnology , staphylococcus aureus , antiseptic , hand sanitizer , chlorine , hydrogen peroxide , biology , disinfectant , sterilization (economics) , methicillin resistant staphylococcus aureus , bacteria , chemistry , food science , biochemistry , organic chemistry , genetics , foreign exchange , monetary economics , economics , foreign exchange market
Procedures of sterilization and disinfection are essential to ensure that medical and surgical instruments will not transmit infectious pathogens to patients. In the present paper, we tested the residual effect of these compounds on biofilm formation and its efficiency in disrupting preformed biofilms using methicillin‐resistant Staphylococcus aureus (MRSA) isolates of the lineage ST239‐SCC mec III. All compounds examined, except 70% alcohol, caused a significant impairment in biofilm formation with concomitant inhibition of cell growth. Among the compounds examined, 10% povidone‐iodine (PVP‐I) was the only antiseptic that exhibited more than 90% reduction of both biofilm formation and dispersion. In the group of sterilants and disinfectants, a formulation containing 7% hydrogen peroxide and 0.2% peracetic acid (HP‐PA), and sodium hypochlorite with 1% active chlorine (NaOCl) were equally effective.