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Genotypes of rotavirus associated with acute gastroenteritis in Seoul, Korea
Author(s) -
Park Sanghun,
Oh Seah,
Lee Jibho,
Park Gunyong,
Choi Sungmin,
Chae Youngzoo,
Kim Hyunsoo
Publication year - 2011
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.2011.00366.x
Subject(s) - rotavirus , acute gastroenteritis , genotype , virology , biology , pediatrics , medicine , virus , gene , genetics
Acute viral gastroenteritis is one of the most common infectious diseases in infants and young children. Rotavirus is mainly important in childhood. The present study determined the detection rate, seasonality and G and P genotypes of rotaviruses in children hospitalized for acute gastroenteritis in Seoul, Korea in 2009. A total of 1,423 stool specimens were screened by ELISA for the presence of rotavirus antigens and the rotavirus‐positive stools genotyped by RT‐PCR. The G genotype was determined for 90% of samples (242/269) and the P genotype for 93.3% (251/269). During the study, 25 G‐P combinations were detected with G1P[8] in 38.3% ( n = 103) and G4P[6] in 5.9% ( n = 16) cases. These data provided information on rotavirus in patients with acute gastroenteritis in Seoul, Korea and provided baseline data to motivate for the implementation of control measures for rotavirus disease.