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IgA antibodies to Chlamydia trachomatis and metabolic syndrome
Author(s) -
Sehnem Luciele,
Bodanese Luiz Carlos,
Repetto Giuseppe,
Staub Henrique L.
Publication year - 2010
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.2010.00281.x
Subject(s) - chlamydia trachomatis , chlamydia , metabolic syndrome , antibody , chlamydiales , immunology , immunoglobulin a , chlamydiaceae , biology , chlamydia trachomatis infection , medicine , immunoglobulin g , physiology , endocrinology , obesity
Chlamydia pneumoniae may trigger atherogenesis. Chlamydia trachomatis (CT) can also induce endothelial activation. However, its role in metabolic syndrome (METS), a proatherogenic entity, has remained unexplored. In this study the frequencies of IgA and IgG anti‐CT antibodies were evaluated by immunoenzymatic assay in METS patients and healthy controls. The survey included 238 individuals (148 with METS). The mean age was 59.7 years. IgA anti‐CT antibodies were found significantly more frequently in METS patients (16.9%) than in controls (5.6%) ( P = 0.015). The role of such IgA response in METS should be further investigated.