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Prevalence of integrons and a new dfrA17 variant in Gram‐negative bacilli which cause community‐acquired infections
Author(s) -
Sandalli Cemal,
Buruk Celal Kurtulus,
Sancaktar Metin,
Ozgumus Osman Birol
Publication year - 2010
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.2009.00197.x
Subject(s) - biology , integron , bacilli , microbiology and biotechnology , pulsed field gel electrophoresis , carriage , antibiotics , gram negative bacteria , antibiotic resistance , antimicrobial , bacteria , genotype , escherichia coli , gene , genetics , medicine , pathology
A hundred and eleven Gram‐negative bacilli from community‐acquired infections were characterized by antimicrobial susceptibility testing, screened for class 1 and 2 integrons, and statistically evaluated for the association between antibiotic profile and the presence of integrons. The frequency with which integrons were harbored was 28.8%. Three E. coli strains contained a dfrA17 variant inserted in a class 1 integron. Results of PFGE indicated that some E . coli strains carrying integrons were clonally related. Carriage of gene cassettes was significantly associated with resistance to certain antibiotics ( P < 0.05).