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Differential response of Vibrio cholerae planktonic and biofilm cells to autoinducer 2 deficiency
Author(s) -
Ali Syed A.,
Benitez Jorge A.
Publication year - 2009
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.2009.00161.x
Subject(s) - vibrio cholerae , biofilm , quorum sensing , microbiology and biotechnology , biology , mutant , vibrionaceae , population , bacteria , gene , genetics , medicine , environmental health
ABSTRACT The formation of biofilm communities enhances the persistence of Vibrio cholerae in aquatic environments. Biofilm production is repressed by the quorum‐sensing regulator HapR in response to the accumulation of CAI‐1 and AI‐2. CAI‐1 is the strongest input signal activating HapR, whereas the role of AI‐2 remains ill‐defined. In the present study, we show that a V. cholerae luxS (AI‐2‐defective) mutant made increased biofilm. Interestingly, cells in the biofilm were more responsive to AI‐2 deficiency than cells from the planktonic population.