Premium
Comparative evaluation of Trichosporon asahii susceptibility using ASTY colorimetric microdilution and CLSI M27‐A2 broth microdilution reference methods
Author(s) -
Kalkanci Ayse,
Mekha Nanthawan,
Poonwan Natteewan,
Makimura Koichi,
Sugita Takashi
Publication year - 2008
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.2008.00056.x
Subject(s) - broth microdilution , antifungal , biology , chromatography , colorimetry , microbiology and biotechnology , chemistry , minimum inhibitory concentration , antibiotics
The in vitro activity of AMPH‐B, 5‐FC, FLCZ, MCZ, ITCZ, and VRCZ against 50 isolates of T. asahii was determined using CLSI M27‐A2 microdilution and ASTY colorimetric methods. Observed agreement ranged from 96 to 100% according to the drug. Overall, the agreement between two methods was 97.7%. The ASTY colorimetric method was thus determined to be comparable to the CLSI reference method when testing the susceptibility of T . asahii to a variety of antifungal agents.