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Study of the Effect of Vaccination on Periodic Structures of Measles Epidemics in Japan
Author(s) -
Sumi Ayako,
Kamo Kenichi,
Ohtomo Norio,
Kobayashi Nobumichi
Publication year - 2007
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.2007.tb03976.x
Subject(s) - measles , vaccination , measles virus , virology , measles vaccine , demography , biology , environmental health , immunology , medicine , sociology
The purpose of this paper is to investigate the effect of vaccination on periodic structures of measles epidemics in Japan. We carried out spectral analysis for time series data of measles notifications collected in Japan. It was confirmed that the interepidemic period, which corresponds to the interval between major epidemics of measles, increases as the vaccination ratio increases. This result was supported by a theory based on a mathematical model for epidemics of infectious diseases. It was suggested that the interepidemic period is useful to estimate the effect of vaccination on measles incidences quantitatively.