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Spread of Community‐Acquired Methicillin‐Resistant Staphylococcus aureus (MRSA) in Hospitals in Taipei, Taiwan in 2005, and Comparison of Its Drug Resistance with Previous Hospital‐Acquired MRSA
Author(s) -
Takano Tomomi,
Saito Kohei,
Teng LeeJene,
Yamamoto Tatsuo
Publication year - 2007
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.2007.tb03949.x
Subject(s) - methicillin resistant staphylococcus aureus , clindamycin , staphylococcus aureus , sccmec , drug resistance , incidence (geometry) , microbiology and biotechnology , medicine , multiple drug resistance , antibiotics , biology , bacteria , physics , optics , genetics
Panton‐Valentine leucocidin (PVL)‐positive methicillin‐resistant Staphylococcus aureus (PVL + MRSA) is an emerging pathogen in the community worldwide. The incidence of PVL + MRSA in Taipei, Taiwan was 23.3% for hospital MRSA. PVL + MRSA was isolated from both outpatients and inpatients. Some PVL + ( mecA + ) strains (36.8%) showed low MIC values (μ2 μg/ml) to oxacillin. A major PVL + MRSA resistance pattern was oxacillin and clindamycin resistance (81%). There was no multidrug resistance over three drugs, in contrast to patient PVL – MRSA with resistance to five drugs as a major resistance pattern. The majority of PVL + MRSA belonged to multilocus sequence (ST) type 59, while PVL – MRSA belonged to ST239, ST59 and ST5. The data suggests that although PVL + CA‐MRSA is isolated at a high incidence from hospitals in Taipei, the drug resistance is mostly selected in the community and less prominent compared with previous PVL – hospital‐acquired MRSA.