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Contribution of Multi‐Antimicrobial Resistance to the Population of Antimicrobial Resistant Escherichia coli Isolated from Apparently Healthy Pigs in Japan
Author(s) -
Harada Kazuki,
Asai Tetsuo,
Kojima Akemi,
Sameshima Toshiya,
Takahashi Toshio
Publication year - 2007
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.2007.tb03937.x
Subject(s) - kanamycin , tetracycline , antimicrobial , trimethoprim , biology , microbiology and biotechnology , oxytetracycline , antibiotic resistance , sulfamethoxazole , escherichia coli , drug resistance , population , antibiotics , medicine , environmental health , genetics , gene
The aim of this study was to clarify the involvement of tetracycline usage in resistance rates against other antimicrobials. Antimicrobial susceptibility testing was carried out on 545 porcine Escherichia coli isolates throughout Japan. As the result of analyzing by regions, resistance rates against kanamycin, oxytetracycline and trimethoprim in the Kanto/Koshinetu district were higher than those in some other districts. High resistance rates against kanamycin or trimethoprim in oxytetracycline‐resistant isolates were also observed in the Kanto/Koshinetu district The prevalence of multi‐antimicrobial resistance through co‐selection of resistances against kanamycin or trimethoprim by tetracycline usage could be the cause of regional differences in these resistances in porcine E. coli . By a communicative surveillance, kanamycin‐ and trimethoprim‐resistance rates were likely to be elevated with tetracycline usage. Thus, usage of specific antimicrobial(s) is a remarkable viewpoint to control antimicrobial resistant bacteria.