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Antimicrobial Activities of Cinnamyl Rifamycin Derivatives, T‐9 and T‐11, against Mycobacterium tuberculosis and Mycobacterium avium Complex (MAC) with Special Reference to the Activities against Intracellular MAC
Author(s) -
Sato Katsumasa,
Shimizu Toshiaki,
Dimova Velitchka,
Tomioka Haruaki
Publication year - 2006
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.2006.tb03836.x
Subject(s) - rifabutin , rifamycin , microbiology and biotechnology , mycobacterium , mycobacterium tuberculosis , biology , rifampicin , antimicrobial , mycobacterium marinum , mycobacterium tuberculosis complex , tuberculosis , antibiotics , bacteria , medicine , genetics , clarithromycin , pathology
The mycobacterial activities of cinamyl rifamycin derivatives, T‐9 and T‐11, especially against extracellular and intracellular Mycobacterium avium complex residing within macrophages and type II pneumocytes were compared with those of other rifamycins. The activities of test rifamycins were found to be in the order rifalazil, rifabutin, T‐9, T‐11, and rifampicin.