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Unnoticed Spread of Class 1 Integrons in Gram‐Positive Clinical Strains Isolated in Guangzhou, China
Author(s) -
Shi Lei,
Zheng Meiping,
Xiao Zenghuang,
Asakura Masahiro,
Su Jianyu,
Li Lin,
Yamasaki Shinji
Publication year - 2006
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.2006.tb03815.x
Subject(s) - integron , biology , gene cassette , microbiology and biotechnology , bacteria , gene , gram , genetics , antibiotic resistance , antibiotics
A total of 46 gram‐positive bacteria isolated from clinical specimens collected in China were subjected to PCR analysis with the intI1 ‐specific primers, and the intI1 ‐positive strains were further analyzed for their resistance gene cassette. All isolates possessed the class 1 integron in their genomes and the array of gene cassettes was dhfrXII‐orfF‐aadA2 , which is very similar to other organisms except in one isolate carrying an additional copy of the class 1 integron containing the aadA2 gene cassette. Altogether, the results indicate that the class 1 integron is widespread in gram‐positive clinical strains isolated in Guangzhou, China.