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Relatedness between the Coagulase Gene 3′‐End Region and Coagulase Serotypes among Staphylococcus aureus Strains
Author(s) -
Kanemitsu Keiji,
Yamamoto Hiroyuki,
Takemura Hiromu,
Kaku Mitsuo,
Shimada Jingoro
Publication year - 2001
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.2001.tb01270.x
Subject(s) - coagulase , biology , phylogenetic tree , serotype , microbiology and biotechnology , staphylococcus aureus , gene , genetics , staphylococcus , bacteria
The 3′‐end region of the coagulase gene from 22 strains of Staphylococcus aureus including 10 standard serotype strains was sequenced, and five subgroups with 48 tandem repeating units were distinguished among the tested strains. Phylogenetic analysis of the 3′‐end region of the coagulase gene indicated that strains belonging to the same serotype were clustered in the same branch. A phylogenetic tree of the deduced amino acid sequences revealed that the C‐terminal region might not be responsible for the epitope of the coagulase protein.