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Intrafamilial Distribution of Mutans Streptococci in Japanese Families and Possibility of Father‐to‐Child Transmission
Author(s) -
Kozai Katsuyuki,
Nakayama Ryusuke,
Tedjosasongko Udijanto,
Kuwahara Satsuki,
Suzuki Junji,
Okada Mitsugi,
Nagasaka Nobuo
Publication year - 1999
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.1999.tb02380.x
Subject(s) - haeiii , biology , serotype , genotype , ecori , microbiology and biotechnology , genetics , streptococcus mutans , transmission (telecommunications) , restriction enzyme , virology , restriction fragment length polymorphism , bacteria , dna , gene , electrical engineering , engineering
The purpose of this study was to investigate the intrafamilial distribution of mutans streptococci in Japanese families using chromosomal DNA fingerprinting with three endonucleases; Eco RI, Hin dIII and Hae III. The analysis of 1,908 isolates cultured from the dental plaque of 76 subjects from 20 families (20 married couples and 36 of their children) resulted in the identification of 144 genotypes containing 114 strains of Streptococcus mutans (serotype c , 66.7%; e , 12.5%) and 30 strains of S. sobrinus (d , 13.2%; g , 7.6%). A mean of 1.89 genotypes (from one to four) was harbored in individual subjects, and a mean of 4.10 genotypes from two to seven was harbored in individual families. Among the 70 genotypes found in the children, 36 (51.4%) were in agreement with their mothers and 22 (31.4%) were in agreement with their fathers. The other genotypes (18.6%) did not correspond with the parents. Homologous strains between parents were found in only two couples. This result showed that fathers or others as well as mothers can be sources of transmission. Further, the serotype d, e and g strains showed significantly higher probabilities of transmission than serotype c .