Premium
In Vitro Susceptibility of Chlamydia pecorum to Macrolides, Tetracyclines, Quinolones and β‐Lactam
Author(s) -
Fukushi Hideto,
Ochiai Yoshitsugu,
Yamaguchi Tsuyoshi,
Hirai Katsuya
Publication year - 1998
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.1998.tb01971.x
Subject(s) - clarithromycin , ofloxacin , ciprofloxacin , erythromycin , ampicillin , minocycline , doxycycline , antibacterial agent , microbiology and biotechnology , roxithromycin , biology , chlamydia , antibiotics , immunology
The in vitro susceptibility of Chlamydia pecorum to two macrolides (clarithromycin and erythromycin), two tetracyclines (doxycycline and minocycline), two quinolones (ofloxacin and ciprofloxacin) and one β‐lactam (ampicillin) was determined. The MICs were 0.004 to 0.008 μg/ml for clarithromycin, 0.008 to 0.031 μg/ml for doxycycline and minocycline, 0.063 to 0.125 μg/ml for erythromycin, 0.25 to 0.5 μg/ml for ofloxacin and 0.25 to 1.0 μg/ml for ciprofloxacin. The MIC for ampicillin was greater than 1,024 μg/ml. The results show clarithromycin and doxycycline are the two most effective drugs against C. pecorum.