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Experimental Dental Caries on Gnotobiotic Inbred Mice
Author(s) -
Maeda Nobuko,
Arai Satoshi,
Ozaki Akira,
Oowada Tsutomu,
Takahashi Akiko,
Fujita Hiroshi,
Mizutani Takeo
Publication year - 1995
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.1995.tb02171.x
Subject(s) - enterococcus faecalis , biology , cecum , microbiology and biotechnology , incidence (geometry) , dentistry , bacteria , medicine , genetics , staphylococcus aureus , ecology , physics , optics
The purpose of this study in mono‐infected gnotobiotic BALB/cA and C3H/HeN mice was to evaluate the cariogenicity of Enterococcus faecalis . The caries incidence and mean caries score in the BALB/cA mice were significantly higher than those in the C3H/HeN. In both of the mouse strains, the mean number of E. faecalis isolated from the cecum content was almost the same, however, the mean number of E. faecalis from the maxilla of BALB/cA was significantly higher than that of C3H/HeN. These results indicate that C3H/HeN has some factors that prevent E. faecalis from attaching to the tooth surfaces.