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An Occurrence of Diarrheal Cases Associated with Group C Rotavirus in Adults
Author(s) -
Oishi Isao,
Yamazaki Kenji,
Minekawa Yoshiichi
Publication year - 1993
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.1993.tb03243.x
Subject(s) - rotavirus , diarrhea , feces , virus , etiology , biology , acute gastroenteritis , virology , acute diarrhea , group a , diarrheal disease , polymerase chain reaction , virus isolation , antibody , reoviridae , immunology , microbiology and biotechnology , gastroenterology , medicine , biochemistry , gene
Six of the 23 college students who joined a group trip in February of 1991 developed acute nonbacterial gastroenteritis with severe diarrhea. The causal agent was identified as group C rotaviruses by electron microscopy (EM), immune‐EM (IEM) and the molecular examinations including polyacrylamide gel electrophoresis (PAGE) and polymerase chain reaction (PCR) on virus particles detected in the extract of watery fecal specimens of the patients. The patients positive for virus isolation showed significant increase in IEM antibody to the isolated virus in their paired sera. These findings suggest that the group C rotavirus is an important etiological agent of diarrhea and may also cause serious food‐borne diarrheal disease in adults.