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Prevalence of Antibodies to Pseudomonas pseudomallei Exotoxin and Whole Cell Antigens in Military Personnel in Sabah and Sarawak, Malaysia
Author(s) -
Embi Noor,
Suhaimi Adlan,
Mohamed Rahmah,
Ismail Ghazally
Publication year - 1992
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.1992.tb02092.x
Subject(s) - exotoxin , antibody , antigen , pseudomonas exotoxin , microbiology and biotechnology , titer , biology , pseudomonas , melioidosis , antibody titer , burkholderia pseudomallei , virology , immunology , bacteria , pseudomonas aeruginosa , toxin , genetics
Sera from 420 military personnel serving in Sabah and Sarawk, Malaysia, were tested for antibodies to Pseudomonas pseudomallei exotoxin and whole cell antigens by enzyme‐linked immunosorbent assay procedure (ELISA). Data showed that 54.4% of serum samples were positive for antibodies to P. pseudomallei exotoxin and 65.7% were positive for antibodies to the whole cell antigens. Samples gave much lower titers for anti‐exotoxin antibodies compared to titers against crude whole cell antigens. The incidence of antibody to exotoxin was highest in the age groups ranging from 26 to 32 years, where the positive rates were higher than 40% and 30% for military personnel serving in Sarawak and Sabah, respectively.