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Genetic Variation among Malaysian Isolates of Salmonella typhi as Detected by Ribosomal RNA Gene Restriction Patterns
Author(s) -
Pang Tikki,
Altwegg Martin,
Martinetti Gladys,
Koh Chong Lek,
Puthucheary Savithri
Publication year - 1992
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.1992.tb02053.x
Subject(s) - biology , ribosomal rna , genetics , gene , genetic variation , variation (astronomy) , rna , evolutionary biology , physics , astrophysics
Genetic variation among Malaysian isolates of Salmonella typhi was determined by analysis of ribosomal RNA gene restriction patterns. Of the 20 isolates analyzed, eight different pattern combinations were detected. The amount of variation observed was also dependent upon the restriction endonuclease used; Pst I produced more different patterns than did Sma I. The results suggested that disease activity was due to a number of different clones circulating simultaneously rather than a single strain. Further implications of the data are discussed.