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An Aberrant Hemolysin of Vibrio cholerae Non‐O1
Author(s) -
Iwanaga Masaaki,
Ichinose Yoshio
Publication year - 1991
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.1991.tb01604.x
Subject(s) - hemolysin , vibrio cholerae , vibrionaceae , biology , microbiology and biotechnology , el tor , strain (injury) , hemolysis , cholera , bacteria , virulence , genetics , gene , immunology , anatomy
An aberrant hemolysin produced by a Vibrio cholerae non‐O1 strain N037 (N037‐hly) was purified and characterized. N037‐Hly was antigenically very similar to E1 Tor hemolysin but differed in molecular weight (48,000 vs. 60,000), interaction with glucose, and hemolytic activity. Of 100 V. cholerae non‐O1 strains other than the N037 strain examined, none produced this aberrant hemolysin. The N‐terminal amino acid sequence of N037‐hly was highly homologous to that of E1 Tor hemolysin.