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Human Immunodeficiency Virus Infection in Cells of Myeloid‐Monocytic Lineage
Author(s) -
Ushijima Hiroshi,
Dairaku Masatake,
Honma Hitoshi,
Yamaguchi Koushi,
Shimizu Hiroyuki,
Tsuchie Hideaki,
Abe Kenji,
Yamamoto Akiko,
Hoshino Hiroo,
Müller Werner E.G.
Publication year - 1991
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.1991.tb01579.x
Subject(s) - biology , cell culture , virology , virus , lymphoma , antigen , thp1 cell line , myeloid , immunology , genetics
We established persistent infection with a strain of human immunodeficiency virus type I, HTLV‐IIIB, in a promyelomonocytic cell line, ML‐1 (CD4 antigen nearly negative and CD4 mRNA negative), and a promonocytic cell line, THP‐1 (CD4 antigen positive). Different reaction of giant cell formation was found after co‐cultivation of infected and uninfected cells of ML‐1, HL‐60, THP‐1 and U‐937 cell lines with uninfected and infected MOLT4 (a T‐lymphoma cell line).