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Enhancement of Natural Resistance of Mice to Rhodococcus equi Infection by Dextran Sulfate 500
Author(s) -
Takai Shinji,
Yokoyama Yasushi,
Tsubaki Shiro
Publication year - 1990
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.1990.tb01046.x
Subject(s) - listeria monocytogenes , dextran , rhodococcus equi , intraperitoneal injection , biology , distribution (mathematics) , microbiology and biotechnology , bacteria , pharmacology , biochemistry , gene , mathematical analysis , genetics , mathematics , virulence
The effect of intraperitoneal injection of Dextran Sulfate 500 (DS‐500, 500,000 Mr) on the intravenous clearance and host resistance to Rhodococcus equi in mice was studied. Contrary to the results seen with Listeria monocytogenes , DS‐500 enhanced murine resistance to R. equi and altered organ distribution and clearance.