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Hemagglutinating Activity of Mycoplasma salivarium and Its Attachment to Sheep Red Blood Cells
Author(s) -
Watanabe Tsuguo,
Shibata Kenichiro,
Yukitake Hideharu
Publication year - 1990
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.1990.tb01026.x
Subject(s) - biology , organism , microbiology and biotechnology , saliva , agglutination (biology) , bivalent (engine) , glycoprotein , mycoplasma , biochemistry , antigen , immunology , chemistry , metal , paleontology , organic chemistry
Mycoplasma salivarium (ATCC 23064) and 10 other strains isolated from human saliva agglutinated red blood cells of rabbits and human types A and O weakly, and those of sheep (SRBC) and human type B strongly. Glycoproteins on the surface of the organism cells and N ‐acetylneuraminic acid residues and some sugars on SRBC were suggested to be involved in agglutination of SRBC. Protein A‐like activity was detected in the organism cells. The organism cells were also shown to attach to SRBC in PPLO broth (Difco) supplemented with 10% horse serum, and bivalent metal ions were suggested to be involved in the attachment. The organism cells attaching to SRBC activated complement through the alternative pathway and lyzed the SRBC.