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An Application of Monoclonal Antibodies to Identification of Leptospires of Serogroup Icterohaemorrhagiae Found in China
Author(s) -
WanHe Zhang,
XiuFen Bai,
DiKai Nie,
QingDong Deng
Publication year - 1989
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.1989.tb03161.x
Subject(s) - serotype , virology , biology , monoclonal antibody , antiserum , leptospira interrogans , leptospirosis , serology , leptospira , typing , antibody , microbiology and biotechnology , immunology
For the purpose of improving the procedures of identification of leptospires, a set of 5 monoclonal antibodies with different serological reactivity against serovars of Leptospira interrogans Icterohaemorrhagiae serogroup isolated in China was developed. One hundred and eight strains isolated from epidemic fields in 5 provinces in southern China were distinctly identified into 4 serovars of Icterohaemorrhagiae serogroup by the monoclonal antibody procedure, i.e., 98 isolates were identified as serovar lai , 7 as icterohaemorrhagiae , 2 as copenhageni , and 1 as H2 . Factor antiserum procedure was used at the same time as control for typing these strains and an identical result was obtained.