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Specific Immunoglobulin Response in Mice Immunized with Porins and Challenged with Salmonella typhi
Author(s) -
Sharma Praveen,
Ganguly Nirmal Kumar,
Sharma Bal Krishan,
Sharma Saroj,
Sehgal Rakesh
Publication year - 1989
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.1989.tb02002.x
Subject(s) - antibody , salmonella typhi , biology , potency , immunology , immunoglobulin m , immunoglobulin a , salmonella , humoral immunity , immunoglobulin g , immunoglobulin e , antibody response , immunization , virology , microbiology and biotechnology , in vitro , bacteria , escherichia coli , biochemistry , genetics , gene
Specific antiporin antibody (IgG, IgM, and IgA) response was studied in control, infected, immunized‐infected, and immunized mice. The activity of specific IgG immunoglobulins was found to be the highest in immunized and immunized‐infected groups in which 87.5% protection had been observed by laboratory potency test in mice; the next‐highest activities were those of IgM and IgA immunoglobulins. However, in the infected group the activity of specific IgM and IgG immunoglobulins was almost similar.