Premium
Susceptibility of Mycobacterium avium and Mycobacterium intracellulare to Various Antibacterial Drugs
Author(s) -
Tomioka Haruaki,
Sato Katsumasa,
Saito Hajime,
Yamada Yoshitaka
Publication year - 1989
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.1989.tb02000.x
Subject(s) - ethambutol , clofazimine , kanamycin , microbiology and biotechnology , rifampicin , mycobacterium , rifabutin , streptomycin , biology , mycobacterium avium intracellulare infection , ofloxacin , ciprofloxacin , antibacterial agent , isoniazid , antibiotics , virology , bacteria , tuberculosis , medicine , clarithromycin , immunology , leprosy , pathology , genetics
Mycobacterium avium and M. intracellulare of human and natural sources, identified by the Gen‐Probe ®Rapid Diagnostic System for M. avium Complex (MAC) were studied for susceptibility to eight different drugs. In the case of human isolates of MAC, the following was noted. M. avium showed nearly the same susceptibility to streptomycin, kanamycin, ethambutol, and clofazimine as was seen with M. intracellulare. M. avium was much more resistant to rifampicin and rifabutin than was M. intracellulare , and M. avium was more susceptible to quinolones such as ofloxacin and ciprofloxacin. Conversely, in the case of MAC from natural sources, there was no difference between the susceptibility of M. avium and M. intracellulare to these antibacterial agents.