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Conjugal Transfer of Beta‐Lactamase‐Producing Plasmids of Neisseria gonorrhoeae to Neisseria meningitidis
Author(s) -
Ikeda Fumiaki,
Tsuji Akiyoshi,
Kaneko Yasuko,
Nishida Minoru,
Goto Sachiko
Publication year - 1986
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.1986.tb03000.x
Subject(s) - neisseria gonorrhoeae , plasmid , neisseria meningitidis , microbiology and biotechnology , neisseriaceae , biology , escherichia coli , neisseria , beta lactamase , bacteria , virology , genetics , gene , antibiotics
Twenty clinical isolates of beta‐lactamase‐producing Neisseria gonorrhoeae from Japanese sources were studied to define their ability to serve as donors for their plasmids in conjugation with Neisseria meningitidis . These twenty strains of N. gonorrhoeae harbored the 4.5‐megadalton (Mdal) beta‐lactamase‐producing plasmids and the 24.5‐Mdal conjugative plasmids. We found that only three of twenty N. gonorrhoeae strains showed a detectable conjugation frequency (>10 ‐5 ) with N. meningitidis as the recipient although all strains were capable of mobilizing beta‐lactamase‐producing plasmids to N. gonorrhoeae and to Escherichia coli . The 4.5‐Mdal beta‐lactamase‐producing plasmid was maintained in N. meningitidis , but the large 24.5‐Mdal conjugative plasmid has not been found in N. meningitidis transconjugants.