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Plasmid Profiles of Neisseria gonorrhoeae in Peninsular Malaysia
Author(s) -
Kalaimathee K.K.,
Koh ChongLek,
Ngeow YunFong
Publication year - 1985
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.1985.tb02957.x
Subject(s) - plasmid , neisseria gonorrhoeae , biology , microbiology and biotechnology , neisseriaceae , beta lactamase , virology , escherichia coli , genetics , gene , antibiotics
The plasmid profiles of 160 strains of Neisseria gonorrhoeae isolated in Peninsular Malaysia, comprising 80 penicillinase‐producing (PPNG) and 80 non‐penicillinase‐producing (non‐PPNG) isolates, were determined. The 80 PPNG isolates were divided into two plasmid groups. All of them harbored two common plasmid species, a 4.4 megadalton (Md) R plasmid previously associated with β‐lactamase production in PPNG strains from the Far East and a 2.6 Md multicopy plasmid of unknown function. In addition to these two plasmids, 60 (75%) PPNG isolates also carried a large 24.5 Md conjugative plasmid. In contrast, the 80 non‐PPNG strains were divided into three plasmid groups. All of them possessed the 2.6 Md cryptic plasmid, and 35 (44%) isolates also harbored the 24.5 Md transfer plasmid. Besides these two plasmids, one non‐PPNG isolate carried an additional 7.8 Md cryptic plasmid.