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Existence of 28R‐Antigen in a Certain Strain of Group F Streptococcus
Author(s) -
Maekawa Shizue,
Yaegashi Tazuko,
Nakayama Yasuhiko
Publication year - 1978
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.1978.tb00371.x
Subject(s) - antigen , pepsin , trypsin , biology , streptococcus , agglutination (biology) , digestion (alchemy) , strain (injury) , microbiology and biotechnology , typing , group a , biochemistry , enzyme , bacteria , chemistry , immunology , chromatography , genetics , medicine , anatomy
An inter‐Group common antigen was detected between Group A type 28 (Small)‐ and Group F (21/58/O'Mahoney, Colindale)‐streptococcal cells by the T‐typing agglutination reaction. The characteristics of this antigen coincide with those of the 28R‐antigen, which was first detected in the Group A type 28 (Small) cells by Lancefield in 1943, in the following points: 1) It can beextract ed from the cells with HCl at pH 2.0 at 100 C in a stable state; 2) It can be kept in a stable state by heating in an alkaline solution at pH 7.8; 3) The antigen on the heat‐killed cells was not affected by trypsin digestion at pH 7.8 but was destroyed by pepsin digestion at pH 2.0.