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R Plasmids among Gram‐Negative Bacteria with Multiple Drug Resistance Isolated in a General Hospital
Author(s) -
Suzuki Satoshi,
Miyoshi Yasushi,
Nakaya Rintaro
Publication year - 1978
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.1978.tb00369.x
Subject(s) - plasmid , biology , drug resistance , microbiology and biotechnology , gram , bacteria , isolation (microbiology) , gram negative bacteria , escherichia coli , genetics , gene
The incidence of conjugative R plasmids in multiple drug‐resistant strains of gram‐negative bacteria isolated in 1973 from patients in a 700‐bed general hospital in Tokyo and some properties of the R plasmids isolated are described. Conjugative R plasmids were found in 52 of the 96 strains (54%), from which 74 R plasmids were demonstrated. It is remarkable that the isolation frequency of R plasmids mediating quadruple‐ or five‐drug resistance was rather low, and the complete pattern of multiple resistance of the original isolates was only rarely transferred by conjugation. These results revealed the existing state of the distribution of R plasmids among hospital strains with multiple drug‐resistance.