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Properties of the Erythrocyte Receptors for Influenza C Virus
Author(s) -
Ohuchi Masanobu,
Homma Morio,
Muramatsu Michiko,
Ohyama Shinobu
Publication year - 1978
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.1978.tb00363.x
Subject(s) - virus , neuraminidase , biology , virology , hemagglutination , receptor , orthomyxoviridae , titer , hemagglutinin (influenza) , influenzavirus b , influenza a virus , hemagglutination assay , antibody dependent enhancement , microbiology and biotechnology , dengue virus , biochemistry
Properties of the receptor for influenza C virus were studied. Although the receptor for influenza C virus on chicken erythrocytes was destroyed by the homologous virion, neuraminidase activity could not be detected in any of the influenza C virus strains tested. The receptor activity of chicken erythrocytes for influenza C virus was diminished by formaldehyde treatment but not by periodate oxidation. There was a considerable variation in the pattern and the titer of hemagglutination of influenza C virus when human erythrocytes of different blood types were used; the virus agglutinated most type B erythrocytes but not type A erythrocytes. By using human type B erythrocytes, differences among strains of influenza C virus in the hemagglutinating activity were also demonstrated. These results showed that both the receptor for and the receptor‐destroying activity of influenza C virus were completely different from those of influenza A or B virus and also that carbohydrates were not involved in the receptor for influenza C virus.