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Failure of the Reaction of β 2 ‐Microglobulin with Staphylococcal Protein A
Author(s) -
Ochi Yukio,
Hachiya Takashi,
Kajita Yoshihiro
Publication year - 1977
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.1977.tb00333.x
Subject(s) - beta 2 microglobulin , biology , peptide sequence , sequence (biology) , amino acid , immunology , biochemistry , gene
Because β 2 ‐microglobulin is structurally similar to IgG, the reaction of β 2 ‐microglobulin with Staphylococcal Protein A, which is known to react with the Fc region of IgG, was examined. 125 I‐β 2 ‐microglobulin did not bind to Protein A. This may due to the difference in the amino acid sequence between β 2 ‐microglobulin and the Fc region of IgG.