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The Ability of Athymic Nude Mice to Survive Intracerebral Infection of Lymphocytic Choriomeningitis (LCM) Virus
Author(s) -
Mori Ryoichi,
Hino Yuwao,
Taniguchi Toru,
Nomoto Kikuo,
Takeya Kenji
Publication year - 1976
Publication title -
japanese journal of microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0021-5139
DOI - 10.1111/j.1348-0421.1976.tb00984.x
Subject(s) - lymphocytic choriomeningitis , virus , virology , biology , delayed hypersensitivity , medicine , immunology , antigen , cd8
Adult athymic nude mice were protected against the lethality of intracerebral infection with LCM virus. Although the multiplication of LCM virus in the brain was almost equal between nu/nu and nu/+ mice, the delayed hypersensitivity reaction was not evoked in nu/nu mice as evidenced by foot pad reaction.