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Replication of Adenovirus 12 Deoxyribonucleic Acid in Association with the Nuclear Membrane
Author(s) -
Yamashita Tadashi,
Shimojo Hiroto
Publication year - 1973
Publication title -
japanese journal of microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0021-5139
DOI - 10.1111/j.1348-0421.1973.tb00793.x
Subject(s) - primer (cosmetics) , nuclear membrane , dna , nuclear dna , dna polymerase , microbiology and biotechnology , dna replication , biology , virology , in vitro , polymerase , chemistry , membrane , biochemistry , gene , organic chemistry , mitochondrial dna
Analysis of nuclei of adenovirus 12‐infected cells revealed that viral DNA replicated in association with the nuclear membrane and that complete viral DNA was liberated from the nuclear membrane. Analysis of isolated nuclei in vitro showed that DNA polymerase activity increased in the nuclear membrane of adenovirus 12‐infected cells without addition of primer DNA.