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Aspartic Acid Transport in Mycobacterium smegmatis
Author(s) -
Yabu Kunihiko
Publication year - 1971
Publication title -
japanese journal of microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0021-5139
DOI - 10.1111/j.1348-0421.1971.tb00603.x
Subject(s) - aspartic acid , mycobacterium smegmatis , glutamic acid , kinetics , chemistry , biochemistry , amino acid , medicine , tuberculosis , pathology , mycobacterium tuberculosis , physics , quantum mechanics
L ‐Aspartic acid was taken up by Mycobacterium smegmatis cells at a greater rate than D ‐aspartic acid. Kinetic studies of L ‐aspartic acid uptake revealed a curvilinear Lineweaver‐Burk plot. The observed kinetics could be accounted for by the existence of two different processes, a saturable and a nonsaturable. In contrast, the latter process was solely active for D ‐aspartic acid uptake. Competition studies indicated that aspartic acid and glutamic acid were similarly affected by the operation of 2 different processes. The existence of 2 similar catalytic transport processes, specific for dicarboxylic amino acids, was discussed.