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Exclusive facial porokeratosis: Histopathologically showing follicular cornoid lamellae
Author(s) -
LEE Yoonhee,
CHOI Eung Ho
Publication year - 2011
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2011.01260.x
Subject(s) - porokeratosis , medicine , dermatology , lesion , histopathological examination , trunk , hyperkeratosis , dyskeratosis , biopsy , pathology , anatomy , biology , ecology
Porokeratosis is a heterogeneous group of disorders that are mostly inherited in an autosomal dominant fashion. It has a wide variety of clinical manifestations with a characteristic histological finding of cornoid lamella. Porokeratosis usually affects the trunk or the extremities. Exclusive facial lesions are rare, although 15% of patients with disseminated, superficial, actinic porokeratosis do have facial lesions. Herein, we discuss the case of a 25‐year‐old woman who noticed the appearance of well‐defined, brownish, macular lesions located on both cheeks. She had no other symptoms. A skin examination showed well‐demarcated, multiple, brownish macules with raised hyperkeratotic borders on both cheeks and a half‐palm‐sized, arcuate‐shaped lesion formed by grouped macules on the right cheek. No other parts of the body were affected. Histopathological examination of a biopsy specimen obtained from the hyperkeratotic margin gave a diagnosis of porokeratosis with follicular involvement of the cornoid lamellae. Topical pimecrolimus was applied twice a day to the lesions, although little improvement was achieved after 2 months.