Premium
Reactive proliferation of endothelial cells and pericytes associated with arteriovenous malformation
Author(s) -
YASUDA Masahito,
OKADA Etsuko,
NAGAI Yayoi,
TAMURA Atsushi,
ISHIKAWA Osamu
Publication year - 2010
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2010.00788.x
Subject(s) - arteriovenous malformation , nodule (geology) , pathology , vascular malformation , differential diagnosis , medicine , abnormality , hemangioma , anatomy , biology , radiology , paleontology , psychiatry
Arteriovenous malformation (AVM) is a structural vascular abnormality with no proliferation of cellular components. We report on a 53‐year‐old man who presented with a 15‐year history of a progressively enlarging nodule on his lower lip. A dark‐reddish, easy‐bleeding nodule diagnosed as AVM was resected to reduce the volume and troublesome bleeding. Histologically, the nodule revealed that the proliferating cellular area was composed of endothelial cells and pericytes in addition to the area of dilated vessels. We speculated that the cell proliferation developed secondary to AVM. We also discuss the histological differential diagnosis of spindle cell hemangioma and pseudo‐Kaposi’s sarcoma.