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Malignant melanoma with preserved hairs: A snap shot could suggest the development from an acquired melanocytic nevus
Author(s) -
KIYOHARA Takahiro,
KOURABA Sachio,
TAKAHASHI Hidenori,
KAWASAKI Takeo,
TAKEUCHI Akiteru,
KUMAKIRI Masanobu
Publication year - 2010
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2009.00780.x
Subject(s) - forehead , nodule (geology) , dermis , melanoma , nevus , melanocytic nevus , epidermis (zoology) , dermatology , pathology , anatomy , medicine , biology , cancer research , paleontology
A 63‐year‐old man presented with a dome‐shaped, black nodule on his right forehead, where hairs were preserved. The black surface tone measured 7 mm in diameter and spread irregularly from the periphery of the nodule. He had been conscious of the preceding, black macule for approximately 50 years. A snap shot of the patient in adolescence showed a tiny, black macule, which was a few millimeters in diameter. Histological examination demonstrated irregular proliferation of melanoma cells from the epidermis to the dermis. Partially, there were well‐circumscribed, oval nests composed of nevus cells in the acanthotic epidermis and follicles. Nevus cells were also seen in the dermal component, presenting a burnt‐out appearance. In this case, the small final size, the preserved hairs and the snap shot suggested a preceding, acquired melanocytic nevus. Malignant melanoma could arise from acquired melanocytic nevus.