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Topical 5‐aminolevulinic acid photodynamic therapy for recalcitrant facial flat wart in Chinese subjects
Author(s) -
LIN MaoYing,
XIANG LeiHong
Publication year - 2008
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2008.00543.x
Subject(s) - photodynamic therapy , medicine , cryotherapy , dermatology , hyperpigmentation , erythema , ablative case , surgery , radiation therapy , chemistry , organic chemistry
The facial flat wart (verruca plana) is not only a contagious viral disease, but also causes a disturbing cosmetic problem. Because 5‐aminolevulinic acid photodynamic therapy has successfully treated human papilloma virus‐related diseases, we employed 20% 5‐aminolevulinic acid and a light emitting diode on three recalcitrant facial flat wart patients. Most lesions achieved complete remission after three or four sessions. However, a few non‐elevated lesions did not respond to this method. An ablative therapeutic mode is required in addition to 5‐aminolevulinic acid photodynamic therapy in such lesions. Therefore, we utilized an Er:YAG laser and 20% 5‐aminolevulinic acid photodynamic therapy for one session and achieved an excellent result. Patients should be informed of the possible side‐effects of this treatment, such as erythema, exfoliation and post‐inflammatory hyperpigmentation, and the requirement for sun protection.