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Elastic fiber staining and cytokeratin 15 expression pattern in trichoepithelioma and basal cell carcinoma
Author(s) -
CHOI Chong Won,
PARK Hyun Sun,
KIM Yeon Kyung,
LEE Seung Ho,
CHO Kwang Hyun
Publication year - 2008
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2008.00510.x
Subject(s) - trichoepithelioma , cytokeratin , basal cell carcinoma , staining , pathology , immunohistochemistry , biology , elastic fiber , basal cell , medicine
Trichoepithelioma (TE) is a benign neoplasm of the skin that resembles basal cell carcinoma (BCC) in its clinical and histological features. In this study, we evaluate the usefulness of elastic fiber staining and cytokeratin 15 expression pattern in terms of distinguishing TE from BCC. Eleven TE and 17 BCC were examined histochemically and immunohistochemically. It was found that BCC contain more elastic fiber than TE, and that more TE show peripheral localization than BCC in cytokeratin 15 expression patterns. The present study shows that elastic fiber staining and cytokeratin 15 expression pattern may aid the differentiation of TE from BCC.