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Immunoglobulin A pemphigus associated with immunoglobulin A gammopathy and lung cancer
Author(s) -
PETROPOULOU Haritini,
POLITIS George,
PANAGAKIS Pantelis,
HATZIOLOU Eftihia,
ARONI Kiriaki,
KONTOCHRISTOPOULOS George
Publication year - 2008
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2008.00481.x
Subject(s) - paraneoplastic pemphigus , pemphigus , medicine , immunoglobulin a , gammopathy , antibody , lung cancer , multiple myeloma , immunology , pathology , paraproteinemias , dermatology , immunoglobulin g , monoclonal , monoclonal antibody , autoantibody
Immunoglobulin (Ig)A pemphigus is a rare disease marked by a vesiculopustular eruption characterized by intercellular IgA deposition in the epidermis. It has clinical and histopathological heterogeneity and encompasses two subgroups: subcorneal pustular dermatosis type and intraepidermal neutrophilic IgA dermatosis type. IgA pemphigus has been rarely associated with monoclonal IgA paraprotein, myeloma and B‐cell lymphoma in the past. We report the first case, to our knowledge, of a 47‐year‐old male patient with a subcorneal pustular dermatosis type of IgA pemphigus associated with IgA gammopathy and lung cancer.