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Lichenoid drug eruption of nails induced by propylthiouracil
Author(s) -
SAITO Marumi,
NAKAMURA Koichiro,
KANEKO Fumio
Publication year - 2007
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2007.00361.x
Subject(s) - propylthiouracil , medicine , dermatology , nail (fastener) , lesion , drug reaction , drug , surgery , dentistry , pharmacology , materials science , thyroid , metallurgy
We present the case of a patient who developed deformities of the fingernails and reddish nodules on the nail beds after administration of propylthiouracil (PTU) for 6 months to treat Grave's disease. Histological examination of the lesion revealed a lichenoid tissue reaction. After withdrawal of PTU, she noticed an improvement in the eruption and the growth of the nails. No recurrence of the eruption was detected after the withdrawal of PTU. Thus, we strongly suggest that this was a rare case of PTU‐induced lichenoid drug eruption of nail.