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A Case of Angiolymphoid Hyperplasia with Eosinophilia (ALHE) of the Upper Lip
Author(s) -
Suzuki Hiromi,
Hatamochi Atsushi,
Horie Masaki,
Suzuki Toshihiro,
Yamazaki Soji
Publication year - 2005
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2005.tb00888.x
Subject(s) - angiolymphoid hyperplasia with eosinophilia , medicine , pathology , nodule (geology) , biopsy , lumen (anatomy) , upper lip , eosinophilia , dermatology , anatomy , surgery , biology , paleontology
Angiolymphoid hyperplasia with eosinophilia (ALHE) is clinically characterized by intradermal or subcutaneous papules and/or nodules usually occurring in young adults. Lesions in the oral mucosa are extremely rare. We report a case and review the literature of ALHE cases involving the oral mucosa. A 40‐year‐old man presented with a painless, 20 × 20 mm, submucosal nodule on the upper lip. Histological examination of lip biopsy specimens revealed an increase in many small vessels. The vascular walls consisted of prominent endothelial cells with a histiocytoid appearance, which protruded into the lumen. Many eosinophils and lymphocytes were also seen around the vessels. The diagnosis of ALHE was made from the above findings.