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Pyoderma Gangrenosum in Association with Juvenile Rheumatoid Arthritis
Author(s) -
Yaylı Savaş,
Bahadır Sevgi,
Alpay Köksal,
Çimşit Gülseren,
Çobanoğlu Ümit,
Tosun Mehmet
Publication year - 2005
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2005.tb00853.x
Subject(s) - pyoderma gangrenosum , medicine , buttocks , juvenile rheumatoid arthritis , dermatology , arthritis , inflammatory bowel disease , dermis , rheumatoid arthritis , lesion , skin biopsy , biopsy , pathology , surgery , disease
A 17‐year‐old girl presented with multiple, painful, erythematous blisters and ulcerated lesions on the shins and buttocks. She also had arthralgia. She had suffered from juvenile rheumatoid arthritis (JRA) and recieved anti‐inflammatory agents and oral glucocorticoids for eight years. A biopsy of a lesion showed epidermal ulceration with marked neutrophilic infiltrates in the dermis. The patient was diagnosed with pyoderma gangrenosum (PG). PG is an uncommon cutaneous ulceration within the spectrum of the neutrophilic dermatoses that is reported in association with a number of systemic disorders, including inflammatory bowel disease, hematologic disease, internal malignancies, arthritis, immune abnormalities, and solid tumors. To our knowledge, this is the first reported case of PG associated with JRA.