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Multiple Plaques on the Back: S‐100 Negative Benign Granular Cell Tumor
Author(s) -
Arican Ozer,
Ciralik Harun,
Sasmaz Sezai
Publication year - 2005
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2005.tb00803.x
Subject(s) - granular cell tumor , pathology , medicine , immunohistochemistry
Granular cell tumor is a rarely seen disease characterized by a gradually developing nodular lesion, which is difficult to diagnose. It has been thought to originate from Schwann cells. The tumor usually appears in the 4th–6th decades of life, more frequently in women and blacks, and has a multifocal location in 10–25% of the cases. The malignancy potential is 1–3%, with 70–74% of the cases in women. Ninety‐eight percent of the cases are S‐100 positive. The present paper describes an 18‐year‐old female patient with benign granular cell tumor. This rarely seen type of tumor was S‐100 negative and has been detected in biopsies taken from multiple asymptomatic plaques and maculopapular lesions. They were 0.5–4 cm in diameter, light brown in color, and with clear contours and had been gradually growing on her back the last nine years.