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Transforming Growth Factor β and Connective Tissue Growth Factor Are Involved in the Evolution of Nevus of Nanta
Author(s) -
Keida Tomoko,
Hayashi Nobukazu,
Kawakami Michiko,
Kawashima Makoto
Publication year - 2005
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2005.tb00776.x
Subject(s) - ossification , connective tissue , dermis , growth factor , nevus , pathology , biology , dermatology , medicine , anatomy , cancer research , genetics , melanoma , receptor
We report a 59‐year‐old Japanese male with nevus of Nanta on the face. Histological examination revealed a nest of nevus cells in the dermis and ossification beneath the nevus. Positive staining for transforming growth factor‐β and connective tissue growth factor suggested the involvement of these growth factors in the ossification of nevus of Nanta.