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Subcutaneous Solitary Fibrous Tumor
Author(s) -
Yoshida Yuichi,
Kubota Yumiko,
Yamaguchi Takahiro,
Iwasaki Hiroshi,
Nakayama Juichiro
Publication year - 2004
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2004.tb00647.x
Subject(s) - solitary fibrous tumor , cd34 , hemangiopericytoma , immunohistochemistry , pathology , differential diagnosis , lesion , anatomy , soft tissue , matrix (chemical analysis) , medicine , biology , chemistry , microbiology and biotechnology , stem cell , chromatography
We describe a unique case of subcutaneous solitary fibrous tumor (SFT) in a 56‐year‐old female patient. The patient had been aware of a painless soft mass in her back for ten years. The lesion was surgically excised. Histological examination revealed that the well‐defined mass was composed of a proliferation of spindle‐shaped fibroblastic cells and polygonal cells embedded in a fibrous matrix corresponding to the so‐called “patternless pattern”. A prominent pericytomatous pattern (hemangiopericytoma‐like structures), focal myxoid changes, and thick hyalinized collagen fibers were also observed. Immunohistochemical stainings for CD34 and bcl‐2 were positive in the tumor cells. These features are compatible with SFT. We suggest that SFT should be included in the differential diagnosis of subcutaneous spindle cell tumors.